[Imageworld] Post-doc position at CMIV, Linköping Univ. , Sweden

[Örjan Smedby]

POST-DOC POSITION AVAILABLE IN MEDICAL IMAGE SCIENCE

The Center for Medical Image Science and Visualization (CMIV) in Linköping, Sweden (http://www.cmiv.liu.se), is a cross-disciplinary research environment comprising researchers within medicine and engineering, aiming at developing, within the imaging and visualization field, new methods for use in clinical routine and medical research. At present, the Center includes about 25 senior researchers and 30 doctoral students, and it has its own premises with state-of-the-art imaging and visualization equipment in Linköping University Hospital.

We are now looking for a post-doc in a project (see below) dealing with quantitative analysis of bone structure in osteoporosis using 3D images from Computed Tomography (CT). The applicant should have a Ph.D. degree in engineering with a good knowledge of image processing. Experience of cross-disciplinary collaboration is a merit.

If interested, please send a written application, quoting the announcement number Dnr LiU 2009-00790, by June 8 to
Linköpings universitet
Registrator
SE-581 83 LINKÖPING
Sweden

For further information you may contact Prof. Örjan Smedby, mailto:orjan.smedby at liu.se, phone +46-13-222717.

The formal announcement (in Swedish) is available at http://www.liu.se/jobbdb/show.html?2964.

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Quantitative assessment in vivo of trabecular bone structure

Osteoporosis is characterised by a change of the trabecular structure of cancellous bone, which may be more important for strength than the reduction of cortical bone. Until now, the 3D microstructure could only be visualised in ex vivo specimens. This project aims at studying this structure in vivo using clinical multislice CT, dual energy CT and dental cone-beam CT.

3D images are acquired, segmented and analyzed with mathematical morphology methods, resulting in measures of trabecular number (Tb.N), mean trabecular separation (Tb.Sp), mean trabecular thickness (Tb.Th), bone volume relative to total volume (BV/TV) and the number of nodules (Tb.Nd) and termini (Tb.Tm). New image analysis methods to better describe the anisotropy of bone will be developed. First, these methods will be compared and validated in specimens using micro-CT as the reference method. Then, they will be tested in vivo in several clinical studies.

The methods developed within this project may have importance for understanding the pathophysiology of osteoporosis, for evaluating the effect of given treatment, and possibly as a screening method.
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*                      Örjan Smedby                       *
*             mailto:orjan.smedby at cmiv.liu.se             *
*                                                         *
*   Dept. of Radiology / CMIV       Tel +46-13-22 27 17   *
*   University Hospital             Fax +46-13-22 17 99   *
*   SE-581 85  Linköping        Mobile +46-702 64 64 00   *
*   Sweden                       http://www.cmiv.liu.se   *
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